[Solution]Type 2 DMPathophysiology

Characterized by hyperglycemia due to impaired insulin resistance as well as a variable degree of impaired insulin secretion • Insulin resistance is characterized by inappropriate…

Characterized by hyperglycemia due to impaired insulin resistance as well as a variable degree of impaired insulin secretion • Insulin resistance is characterized by inappropriate hepatic glucose production and decreased muscle glucose uptake • Unlike Type 1, not prone to ketosis, except under severe conditions

Diagnosis –Current ADA criteria Any one of the following:

HbA1C level >6.5%

Fasting glucose >126 mg/dL

Random glucose >200 in an individual with symptoms of hyperglycemia

Glucose tolerance testing

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